Fulvestrant
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an... more
Product information "Fulvestrant"
Description: Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30. Fulvestrant has antitumor activity, inhibiting cell proliferation and inducing apoptosis and autophagy. Target: Autophagy, Estrogen/progestogen Receptor, Estrogen Receptor/ERR, Apoptosis. Smiles: [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3C[C@@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)[C@@]21[H]. References: Nukatsuka M, et al. Estrogen Down-regulator Fulvestrant Potentiates Antitumor Activity of Fluoropyrimidine in Estrogen-responsive MCF-7 Human Breast Cancer Cells. In Vivo. 2019 Sep-Oct,33(5):1439-1445.
| Keywords: | ZM 182780, ZD 9238, ICI 182780 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2146 |
Properties
| MW: | 606.77 D |
| Formula: | C32H47F5O3S |
Database Information
| CAS : | 129453-61-8| Matching products |
| Protein Atlas Nr. : | Apoptosis, Cell Cycle, DNA Repair |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H362, H413 |
| P Phrases: | P201, P202, P260, P263, P264, P270, P273, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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