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Description: FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces ferroptosis in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer. Target: Ferroptosis. Smiles: COC1=CC=C(C=C1)N1CCN(CC2=CN3C(S2)=NN=C3C2=CC=C(Br)C=C2)CC1. References: Hendricks JM, et, al. Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis. Cell Chem Biol. 2023 May 4:S2451-9456(23)00114-9.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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