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Description: Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds beta-tubulin (Kd: 0.4 µM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50: 2.4 µM), and also disrupts tumor vasculature. Target: Microtubule Associated, Apoptosis. Smiles: [Na+].[Na+].COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OP([O-])([O-])=O. References: Woods JA, et al. Br J Cancer 1995, 71(4), 705-711.
Keywords:
CA 4DP, Combretastatin A4 Phosphate, Combretastatin A4 disodium phosphate, CA 4P, Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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