Flumequine-13C3

Flumequine-13C3 is intended for use as an internal standard for the quantification of flumequine (Cay-21645) by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic. It is active against S. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, and K. pneumoniae (MICs = 1-100 µg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 µg/ml). It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication. In vivo, flumequine (50 mg/kg) increases survival in rat models of P. vulgaris-induced urinary tract infection and P. mirabilis-induced prostatitis. Formulations containing flumequine have been used in the treatment of urinary tract infections in veterinary medicine.Formal Name: 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic-1,2-13C2 acid-13C. CAS Number: 1185049-09-5. Synonyms: (±)-Flumequine-13C3, R-802-13C3. Molecular Formula: C11[13C]3H12FNO3. Formula Weight: 264.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile:Methanol (1:1): soluble, DMSO: soluble. SMILES: O=[13C]1C2=CC(F)=CC3=C2N(C(CC3)C)C=[13C]1[13C](O)=O. InChi Code: InChI=1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)/i11+1,13+1,14+1. InChi Key: DPSPPJIUMHPXMA-AIGZGMKWSA-N.