Fenebrutinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Fenebrutinib (GDC-0853) is a selective and noncovalent inhibitor of Bruton's... more
Product information "Fenebrutinib"
Description: Fenebrutinib (GDC-0853) is a selective and noncovalent inhibitor of Bruton's tyrosine kinase (Btk) with a Ki of 0.91 nM. Target: BTK. Smiles: C[C@H]1CN(CCN1c1ccc(Nc2cc(cn(C)c2=O)-c2ccnc(N3CCn4c5CC(C)(C)Cc5cc4C3=O)c2CO)nc1)C1COC1. References: Erickson RI , et al. Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats. J Pharmacol Exp Ther. 2017 Jan,360(1):226-238.
| Keywords: | GDC-0853 |
| Supplier: | TargetMol |
| Supplier-Nr: | TQ0242 |
Properties
| Application: | Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK) |
| MW: | 664.8 D |
| Formula: | C37H44N8O4 |
Database Information
| CAS : | 1434048-34-6| Matching products |
| KEGG ID : | K07370 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H317, H318, H334, H335, H341, H361, H370, H413 |
| P Phrases: | P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P284, P310, P312, P321, P302+P352, P304+P340, P304+P341, P305+P351+P338, P308+P311, P308+P313, P332+P313, P333+P313, P342+P311, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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