Fenbendazole

Fenbendazole is a benzimidazole anthelmintic. It is active against Giardia in vitro (IC50 = 0.3 µM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. Fenbendazole also activates HIF-1alpha and prevents oxidative stress-induced death in primary neurons in vitro.Formal Name: N-[6-(phenylthio)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester. CAS Number: 43210-67-9. Synonyms: Methyl 5-(phenylthio)-2-benzimidazolecarbamate. Molecular Formula: C15H13N3O2S. Formula Weight: 299.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/mL, DMSO: 10 mg/mL. lambdamax: 218, 296 nm. SMILES: O=C(OC)NC1=NC2=CC(SC3=CC=CC=C3)=CC=C2N1. InChi Code: InChI=1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19). InChi Key: HDDSHPAODJUKPD-UHFFFAOYSA-N.