Farnesyl Pyrophosphate (ammonium salt)

Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 µM), attenuating platelet aggregation. It has also been shown to regulate adipocyte function as an endogenous PPARgamma agonist. Additionally, because of a flexible hydrocarbon chain that enables different conformations, FPP is a promiscuous ligand for a subset of nuclear receptors.Formal Name: P-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester-diphosphoric acid, triammonium salt. CAS Number: 116057-57-9. Synonyms: FPP. Molecular Formula: C15H25O7P2 . 3NH4. Formula Weight: 433.4. Purity: >95%. Formulation: (Request formulation change), A solution in methanol:ammonium hydroxide (70:30). Solubility: Methanol:NH4OH (70:30): * 1 mg/ml. SMILES: C/C(C)=C/CC/C(C)=C/CC/C(C)=C/COP(OP([O-])([O-])=O)([O-])=O.[NH4+].[NH4+].[NH4+]. InChi Code: InChI=1S/C15H28O7P2.3H3N/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18,,,/h7,9,11H,5-6,8,10,12H2,1-4H3,(H,19,20)(H2,16,17,18),3*1H3/b14-9+,15-11+,,,. InChi Key: GSWRJNPTNZUHOV-VLCVYXDNSA-N.