F1063-0967

F1063-0967 is an inhibitor of dual-specificity phosphatase 26 (DUSP26, IC50 = 11.62 µM). It induces IMR-32 neuroblastoma cell apoptosis (IC50 = 4.13 µM).Formal Name: 2-hydroxy-4-[[6-[5-[(4-methylphenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinyl]-1-oxohexyl]amino]-benzoic acid. CAS Number: 613225-56-2. Molecular Formula: C24H24N2O5S2. Formula Weight: 484.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 2 mg/ml, DMSO: 2 mg/ml, Ethanol: slightly soluble. lambdamax: 275, 303, 384 nm. SMILES: O=C(C1=CC=C(NC(CCCCCN2C(SC(C2=O)=CC3=CC=C(C)C=C3)=S)=O)C=C1O)O. InChi Code: InChI=1S/C24H24N2O5S2/c1-15-6-8-16(9-7-15)13-20-22(29)26(24(32)33-20)12-4-2-3-5-21(28)25-17-10-11-18(23(30)31)19(27)14-17/h6-11,13-14,27H,2-5,12H2,1H3,(H,25,28)(H,30,31). InChi Key: RNICWTYEMLCCAS-UHFFFAOYSA-N.