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Description: F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases. Target: PGE Synthase. Smiles: O=C(NC1=CC=C(C=C1)N2C(=O)CCC2)C=3C=NC(=NC3)C4=NC=CC=C4. References: Takaya D, et al. Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies[J]. Bioorganic & Medicinal Chemistry, 2018, 26(16): 4726-4734.
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