(+)-Evodiamine

Evodiamine is a natural indole alkaloid found in the fruits of Wu Zhu Yu, a plant used in traditional Chinese medicine. Studies involving evodiamine have demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions. It can act as an aryl hydrocarbon antagonist (Ki = 28 nM), activator of the transient receptor potential vanilloid 1 channel (EC50 = 45 nM), and inhibit signaling through NF-kappaB.Formal Name: 8,13,13bS,14-tetrahydro-14-methyl-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one. CAS Number: 518-17-2. Synonyms: D-Evodiamine. Molecular Formula: C19H17N3O. Formula Weight: 303.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 1 mg/ml. lambdamax: 224, 270 nm. SMILES: O=C1C2=CC=CC=C2N(C)[C@@]3([H])N1CCC4=C3NC5=C4C=CC=C5. InChi Code: InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3/t18-/m0/s1. InChi Key: TXDUTHBFYKGSAH-SFHVURJKSA-N.