Everolimus
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used... more
Product information "Everolimus"
Description: Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors. Target: Others, Autophagy, mTOR, Apoptosis. Smiles: [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OCCO)[C@@H](C1)OC. References: Zhu Y, et al. Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo. Tumour Biol. 2012 Oct,33(5):1349-62.
| Keywords: | SDZ-RAD, RAD001 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1784 |
Properties
| Application: | Targets serine/threonine-protein kinase mTOR [EC:2.7.11.1] (MTOR, FRAP, TOR) |
| MW: | 958.22 D |
| Formula: | C53H83NO14 |
Database Information
| CAS : | 159351-69-6| Matching products |
| KEGG ID : | K07203 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H372 |
| P Phrases: | P260, P264, P270, P314, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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