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![Everolimus Solution](https://www.biomol.com/media/image/c5/ca/2e/CDX-E0574-M001_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CDX-E0574-M001 | 1 ml | - | - |
3 - 9 business days* |
230.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Liquid. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.22. Macrolide antibiotic,... more
Product information "Everolimus Solution"
Liquid. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.22. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 (FKBP-12) to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin (mTOR). More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo. This compound can be used as a reference material.
Keywords: | 42-O-(2-Hydroxyethyl)rapamycin, NVP-RAD001, RAD001, SDZRAD, Zortress, Afinitor, Certican, Votubia |
Supplier: | Chemodex |
Supplier-Nr: | E0574 |
Properties
MW: | 958,22 D |
Formula: | C53H83NO14 |
Purity: | >99% (HPLC) |
Format: | Liquid |
Database Information
CAS : | 159351-69-6| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
![]() ![]() |
H Phrases: | H225, H319, H302+H332 |
P Phrases: | P210, P305+P351+P338 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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