Ethyl Orsellinate

Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid (Cay-22710) that has antiproliferative activities. It inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively). Ethyl orsellinate is toxic to brine shrimp (A. salina) with an LC50 value of 495 µM.Formal Name: 2,4-dihydroxy-6-methyl-benzoic acid, ethyl ester. CAS Number: 2524-37-0. Synonyms: NSC 149781. Molecular Formula: C10H12O4. Formula Weight: 196.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 0.1 mg/ml. lambdamax: 217, 265, 302 nm. SMILES: CC1=C(C(OCC)=O)C(O)=CC(O)=C1. InChi Code: InChI=1S/C10H12O4/c1-3-14-10(13)9-6(2)4-7(11)5-8(9)12/h4-5,11-12H,3H2,1-2H3. InChi Key: UQSRXQMIXSZGLA-UHFFFAOYSA-N.