Erythromycylamine

Erythromycylamine is a macrolide antibiotic and an active metabolite of dirithromycin (Cay-19466). It is active against a variety of bacteria, including strains of S. pyogenes, S. pneumoniae, L. monocytogenes, and B. pertussis (MICs = 0.06-0.12, 0.06-0.12, 1-2, and 0.015-0.25 µg/ml, respectively). It is also active against 28 clinical isolates of M. avium complex (MAC) isolated from patients with AIDS (MICs = 4-16 µg/ml). Erythromycylamine inhibits polylysine and polyproline synthesis in a cell-free assay.Formal Name: (9S)-9-amino-9-deoxo-erythromycin. CAS Number: 26116-56-3. Synonyms: BRL 42852ER, 9(S)-Erythromycylamine, LY024410. Molecular Formula: C37H70N2O12. Formula Weight: 735.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 15 mg/ml, DMSO: 15 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 269 nm. SMILES: C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@H]2C)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)[C@H](N)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC2=O)([H])O1. InChi Code: InChI=1S/C37H70N2O12/c1-14-25-37(10,45)30(41)20(4)27(38)18(2)16-35(8,44)32(51-34-28(40)24(39(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-32,34,40-42,44-45H,14-17,38H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1. InChi Key: XCLJRCAJSCMIND-JCTYMORFSA-N.