Emodin

Orange solid. Soluble in DMSO or 100% ethanol. Insoluble in water. p56lck protein kinase inhibitor, Competitive casein kinase II (CK2) inhibitor, Anticancer agent with apoptosis inducing with antiangiogenic activity, Antioxidant, vasorelaxant and neuroprotective agent, NF-kappaB activation inhibitor, Inflammasome inhibitor, Potent selective 11beta-HSD1 inhibitor. Improves insulin sensitivity and lipid metabolism, Estrogen receptor ERalpha and ERbeta inhibitor, Inhibits androgen receptor (AR) nuclear translocation and induces AR degradation, VEGFR2, FGFR-1, EGFR, PDGFR-beta and Kit inhibitor, JAK2 inhibitor, Anti-diabetic agent, AMPK activator and PPARgamma agonist. Adipogenesis inhibitor, P2X7 receptor antagonist, Wnt signaling &, PI3K/Akt/GSK-3beta pathway modulator.