Eltanexor

Item number	Size	Delivery time	Price
TGM-T11766L-1mg	1 mg	7 - 10 business days*	60.00€
TGM-T11766L-2mg	2 mg	7 - 10 business days*	108.00€
TGM-T11766L-1mL	1 ml	7 - 10 business days*	226.00€
TGM-T11766L-5mg	5 mg	7 - 10 business days*	237.00€
TGM-T11766L-10mg	10 mg	7 - 10 business days*	288.00€
TGM-T11766L-25mg	25 mg	7 - 10 business days*	474.00€
TGM-T11766L-50mg	50 mg	7 - 10 business days*	674.00€
TGM-T11766L-100mg	100 mg	7 - 10 business days*	978.00€
TGM-T11766L-500mg	500 mg	7 - 10 business days*	1,922.00€

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Description: Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has... more

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Product information "Eltanexor"

Description: Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines. Target: Others. Smiles: NC(=O)C(=C\n1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)\c1cncnc1. References: Vercruysse T et al. The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia. Clin Cancer Res. 2016 Oct 25.

Keywords:	ATG-016, KPT-8602, ONO-7706
Supplier:	TargetMol
Supplier-Nr:	T11766L

Properties

Application:	Targets exportin-1 (XPO1, CRM1)
MW:	428.29 D
Formula:	C17H10F6N6O

Database Information

CAS :	1642300-52-4\| Matching products
KEGG ID :	K14290 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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