Eact
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Eact is a selective and potent TMEM16A activator that directly activates the TRPV1... more
Product information "Eact"
Description: Eact is a selective and potent TMEM16A activator that directly activates the TRPV1 channels in sensory nociceptors, thereby producing itch, acute nociception, and thermal hypersensitivity (brackets). Target: Chloride channel. Smiles: COCCN(C(=O)c1cc(OC)c(OC)c(OC)c1)c1nc(cs1)-c1ccccc1. References: Liu S, et al. Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviours. Br J Pharmacol. 2016 Apr,173(7):1208-18.
| Supplier: | TargetMol |
| Supplier-Nr: | T15192 |
Properties
| Application: | ANO1 activator |
| MW: | 428.5 D |
| Formula: | C22H24N2O5S |
Database Information
| CAS : | 461000-66-8| Matching products |
| KEGG ID : | K19496 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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