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![(E/Z)-4-hydroxy Tamoxifen-d5](https://www.biomol.com/media/image/3f/03/8f/Cay34232-1_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay34232-500 | 500 µg | - |
6 - 10 business days* |
238.00€
|
|||
Cay34232-1 | 1 mg | - |
6 - 10 business days* |
450.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
(E/Z)-4-hydroxy Tamoxifen-d5 is intended for use as an internal standard for the quantification... more
Product information "(E/Z)-4-hydroxy Tamoxifen-d5"
(E/Z)-4-hydroxy Tamoxifen-d5 is intended for use as an internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen (Cay-17308) by GC- or LC-MS. (E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the formation of autophagic vesicles in MCF-7 cells in a superoxide-dependent manner.Formal Name: 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl-3,3,4,4,4-d5]-phenol. CAS Number: 2470232-57-4. Synonyms: Afimoxifene-d5, 4-OHT-d5. Molecular Formula: C26H24D5NO2. Formula Weight: 392.6. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble. SMILES: OC1=CC=C(C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)C([2H])([2H])C([2H])([2H])[2H])C=C1. InChi Code: InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/i1D3,4D2. InChi Key: TXUZVZSFRXZGTL-SGEUAGPISA-N.
Keywords: | 4-OHT-d5, Afimoxifene-d5, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl-3,3,4,4,4-d5]-phenol |
Supplier: | Cayman Chemical |
Supplier-Nr: | 34232 |
Properties
Application: | GC-MS-LC-MS, internal standard, quantification, estrogen receptor agonist/antagonist |
MW: | 392.6 D |
Formula: | C26H24D5NO2 |
Purity: | >99% deuterated forms (d1-d5) |
Format: | Solid |
Database Information
CAS : | 2470232-57-4| Matching products |
KEGG ID : | K08551 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
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H Phrases: | H302, H312, H332, H361 |
P Phrases: | P201, P202, P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P308+P313, P361+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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