(E)-5-(2-Bromovinyl)uracil

Item number	Size	Manual	Delivery time	Price
TGM-T35439-25mg	25 mg	-	7 - 10 business days*	154.00€
TGM-T35439-50mg	50 mg	-	7 - 10 business days*	259.00€
TGM-T35439-100mg	100 mg	-	7 - 10 business days*	478.00€
TGM-T35439-250mg	250 mg	-	7 - 10 business days*	733.00€

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Description: (E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of... more

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Product information "(E)-5-(2-Bromovinyl)uracil"

Description: (E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU), which can be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner, enhancing the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil in a P388 murine leukemia model when administered at a dose of 200 µmol/kg, thereby increasing survival time. Target: Others. Smiles: C(=C/Br)\C=1C(=O)NC(=O)NC1

Supplier:	TargetMol
Supplier-Nr:	T35439

Properties

MW:	217.02 D
Formula:	C6H5BrN2O2

Database Information

CAS :

69304-49-0| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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