E-4031
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs... more
Product information "E-4031"
Description: E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM). Target: EGFR, Potassium Channel. Smiles: Cl.Cl.Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1. References: David Z , Julia B , Gerlind F , et al. Pronounced Effects of HERG-Blockers E-4031 and Erythromycin on APD, Spatial APD Dispersion and Triangulation in Transgenic Long-QT Type 1 Rabbits[J]. PLoS ONE, 2014, 9(9):e107210-.
| Supplier: | TargetMol |
| Supplier-Nr: | T7198 |
Properties
| Application: | ERG K+ channel blocking |
| MW: | 474.44 D |
| Formula: | C21H29Cl2N3O3S |
Database Information
| CAS : | 113559-13-0| Matching products |
| KEGG ID : | K04905 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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