DS44960156

DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2, IC50 = 1.6 µM). It is selective for MTHFD2 over MTHFD1 (IC50 = >30 µM).Formal Name: 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]-benzoic acid. CAS Number: 2361327-08-2. Molecular Formula: C20H15NO5. Formula Weight: 349.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 5 mg/ml, Methanol: Soluble. lambdamax: 272 nm. SMILES: O=C1C2=C(CCN(C(C3=CC=C(C(O)=O)C=C3)=O)C2)C4=C(C=CC=C4)O1. InChi Code: InChI=1S/C20H15NO5/c22-18(12-5-7-13(8-6-12)19(23)24)21-10-9-14-15-3-1-2-4-17(15)26-20(25)16(14)11-21/h1-8H,9-11H2,(H,23,24). InChi Key: OXUKTNZACAKVRG-UHFFFAOYSA-N.