DQP1105

DQP1105 is an NMDA receptor antagonist. It selectively inhibits glutamate-induced currents in Xenopus oocytes expressing rat NR2C and NR2D subunit-containing NMDA receptors (IC50s = 8.5 and 2.7 µM, respectively) over NR2A, NR2B, NRA1, and NRK2 subunit-containing receptors (IC50s = 206, 121, 198, and 153 µM, respectively).Formal Name: 5-(4-bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-gamma-oxo-1H-pyrazole-1-butanoic acid. CAS Number: 380560-89-4. Molecular Formula: C29H24BrN3O4. Formula Weight: 558.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: >50 mg/ml. lambdamax: 232 nm. SMILES: CC1=CC=C2C(C(C3=CC=CC=C3)=C(C4=NN(C(CCC(O)=O)=O)C(C5=CC=C(Br)C=C5)C4)C(N2)=O)=C1. InChi Code: InChI=1S/C29H24BrN3O4/c1-17-7-12-22-21(15-17)27(19-5-3-2-4-6-19)28(29(37)31-22)23-16-24(18-8-10-20(30)11-9-18)33(32-23)25(34)13-14-26(35)36/h2-12,15,24H,13-14,16H2,1H3,(H,31,37)(H,35,36). InChi Key: MVYNQMRZRULRIE-UHFFFAOYSA-N.