Doxepin hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a... more
Product information "Doxepin hydrochloride"
Description: Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors. Target: AChR, Norepinephrine, Adrenergic Receptor, 5-HT Receptor, Dopamine Receptor, Histamine Receptor, P450. Smiles: Cl.CN(C)CCC=C1c2ccccc2COc2ccccc12. References: Ehlert FJ, et al. J Pharmacol Exp Ther. 1990 Apr,253(1):13-9.
| Keywords: | Doxepin HCl, Toruan, Novoxapin, Aponal |
| Supplier: | TargetMol |
| Supplier-Nr: | T1540 |
Properties
| Application: | Targets histamine receptor H1 (HRH1) |
| MW: | 315.837 D |
| Formula: | C19H22ClNO |
Database Information
| CAS : | 1229-29-4| Matching products |
| KEGG ID : | K04149 | Matching products |
| Protein Atlas Nr. : | GPCR Modulators/A(nta)gonists |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P321, P330, P301+P310, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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