Dovitinib lactate hydrate

Dovitinib lactate hydrate
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T6479-5mg 5 mg

7 - 10 business days*

49.00€
TGM-T6479-1mL 1 ml

7 - 10 business days*

49.00€
TGM-T6479-10mg 10 mg

7 - 10 business days*

75.00€
TGM-T6479-25mg 25 mg

7 - 10 business days*

142.00€
TGM-T6479-50mg 50 mg

7 - 10 business days*

242.00€
TGM-T6479-100mg 100 mg

7 - 10 business days*

403.00€
TGM-T6479-200mg 200 mg

7 - 10 business days*

587.00€
 
Description: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a... more
Product information "Dovitinib lactate hydrate"
Description: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. Target: FLT, PDGFR, VEGFR, FGFR, c-Kit. Smiles: O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O. References: Trudel S, et al. Blood, 2005, 105(7), 2941-2948.
Keywords: Dovitinib (TKI258) Lactate, Dovitinib Lactate, TKI258
Supplier: TargetMol
Supplier-Nr: T6479

Properties

Application: Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135)
MW: 482.51 D
Formula: C24H27FN6O4

Database Information

CAS : 915769-50-5| Matching products
KEGG ID : K05089 | Matching products
Protein Atlas Nr. : Tyrosine Phosphorylation

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H341, H351, H361, H372, H400, H410
P Phrases: P201, P202, P260, P264, P270, P273, P280, P314, P330, P391, P301+P310, P308+P313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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