Dovitinib lactate hydrate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a... more
Product information "Dovitinib lactate hydrate"
Description: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. Target: FLT, PDGFR, VEGFR, FGFR, c-Kit. Smiles: O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O. References: Trudel S, et al. Blood, 2005, 105(7), 2941-2948.
| Keywords: | Dovitinib (TKI258) Lactate, Dovitinib Lactate, TKI258 |
| Supplier: | TargetMol |
| Supplier-Nr: | T6479 |
Properties
| Application: | Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135) |
| MW: | 482.51 D |
| Formula: | C24H27FN6O4 |
Database Information
| CAS : | 915769-50-5| Matching products |
| KEGG ID : | K05089 | Matching products |
| Protein Atlas Nr. : | Tyrosine Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H341, H351, H361, H372, H400, H410 |
| P Phrases: | P201, P202, P260, P264, P270, P273, P280, P314, P330, P391, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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