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Description: Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic beta-cell function in type 2 diabetes. Target: Glucokinase. Smiles: CC(C)C[C@H](N1CC(Oc2ccccc2Cl)=CC1=O)C(=O)Nc1ccn(C[C@@H](O)CO)n1. References: Zhu XX, et al. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic beta-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection. Diabetes Obes Metab. 2018 Sep,20(9):2113-2120.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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