Dorsomorphin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and... more
Product information "Dorsomorphin"
Description: Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity. Target: Autophagy, AMPK, TGF-beta/Smad. Smiles: C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1. References: Li N, et al. Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels. Cancer Biol Med. 2019 May,16(2):220-233.
| Keywords: | Compound C, BML-275 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1977 |
Properties
| Application: | AMPK inhibitor, autophagy inducer |
| MW: | 399.49 D |
| Formula: | C24H25N5O |
Database Information
| CAS : | 866405-64-3| Matching products |
| KEGG ID : | K07198 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H312, H332 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P312, P321, P330, P361+364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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