Docetaxel

Docetaxel
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CDX-D0371-M005 5 mg - -

3 - 9 business days*

46.00€
CDX-D0371-M025 25 mg - -

3 - 9 business days*

138.00€
 
White to off-white powder. Soluble in DMSO or ethanol. Chemical. CAS: 114977-28-5. Formula:... more
Product information "Docetaxel"
White to off-white powder. Soluble in DMSO or ethanol. Chemical. CAS: 114977-28-5. Formula: C43H53NO14. MW: 807.88. Synthetic. Anticancer agent. Semisynthetic analog of taxol (paclitaxel). Inhibits microtubule disassembly and inhibits cell replication. Binds to and stabilizes the beta-tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest at G2/M and apoptosis. This cytotoxic activity has been widely exploited in suppressing oncogenic proliferation. Displays potent and broad antineoplastic properties, used mainly for the treatment of breast, ovarian, and non-small cell lung cancer. Also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Also studied for use as a radiation-sensitizing agent.
Keywords: Taxotere(R), NSC 628503, RP 56976, N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
Supplier: Chemodex
Supplier-Nr: D0371

Properties

MW: 807,88 D
Formula: C43H53NO14
Purity: >97% (HPLC)
Format: Solid

Database Information

CAS : 114977-28-5| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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