Diuron

Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. It decreases total respiration in roots of wheat by 50% and ground respiration by 100% when used at a concentration of 25 nM/ml. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively. It increases the production of reactive oxygen species (ROS) in MCF-7 human breast adenocarcinoma and BeWo human placental choriocarcinoma cells when used at a concentration of 200 µM and reduces viability of BeWo, but not MCF-7, cells when used at concentrations of 50 and 200 µM. Formulations containing diuron have been used to control broadleaf and grass weeds and as a biocidal antifouling agent.Formal Name: N'-(3,4-dichlorophenyl)-N,N-dimethyl-urea. CAS Number: 330-54-1. Synonyms: DCMU, NSC 8950. Molecular Formula: C9H10Cl2N2O. Formula Weight: 233.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly Soluble, Methanol: Slightly Soluble. SMILES: ClC1=C(Cl)C=CC(NC(N(C)C)=O)=C1. InChi Code: InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14). InChi Key: XMTQQYYKAHVGBJ-UHFFFAOYSA-N.