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Dimaprit is a histamine H2 receptor agonist with a Ki value of 44 µM in guinea pig right atrium. It is selective for histamine H2 over H1 and H3 receptors with relative potencies of 71, A. suum extract, which is not affected by pretreatment with mepyramine (Cay-20978), an H1 receptor inverse agonist, or cimetidine (Cay-18743), an H2 receptor antagonist. It stimulates gastric acid secretion in vivo in anaesthetized rats and cats with relative potencies of 19.5 and approximately 400 to 500, respectively, compared to histamine. Dimaprit inhibits 2-(2-pyridyl)ethylamine-induced bronchoconstriction in guinea pigs in a dose-dependent manner.Formal Name: carbamimidothioic acid, 3-(dimethylamino)propyl ester, dihydrochloride. CAS Number: 23256-33-9. Molecular Formula: C6H15N3S . 2HCl. Formula Weight: 234.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml. SMILES: NC(SCCCN(C)C)=N.Cl.Cl. InChi Code: InChI=1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8,,/h3-5H2,1-2H3,(H3,7,8),2*1H. InChi Key: DFWCPLGXFMSUCW-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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