Difenoconazole

Difenoconazole is a triazole fungicide. It is active against eight F. graminearum isolates (EC50s = 1.69-19.6 mg/L) and A. sonali, F. fulva, B. cinerea, and R. solani (EC50s = 0.131, 0.069, 0.297, and 0.252 mg/L, respectively). Difenoconazole is active against A. caricae (EC50 = 2 ppm) and reduces the number of leaf and fruit black spots, as well as decreases leaf drop, in papaya plants when applied thirteen times at a rate of 100 g/ha. It is lethal to water fleas (LC50 = 0.298 µg/ml) and zebrafish embryos, larvae, and adults (LC50s = 2.34, 1.17, and 1.45 mg/L, respectively). Difenoconazole induces pericardial and yolk sac edema in zebrafish embryos, body blackening and slowed heart rate in larvae, and decreased body weight and length in adults in a concentration-dependent manner. Formulations containing difenoconazole have been used as fungicides in agriculture, as well as in commercial, industrial, and residential areas.Formal Name: 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole. CAS Number: 119446-68-3. Synonyms: CGA 169374. Molecular Formula: C19H17Cl2N3O3. Formula Weight: 406.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: ClC1=CC=C(OC2=CC(Cl)=C(C3(CN4C=NC=N4)OC(C)CO3)C=C2)C=C1. InChi Code: InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3. InChi Key: BQYJATMQXGBDHF-UHFFFAOYSA-N.