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![Dienestrol](https://www.biomol.com/media/image/52/98/77/Cay38954-100_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay38954-100 | 100 mg | - |
6 - 10 business days* |
93.00€
|
|||
Cay38954-250 | 250 mg | - |
6 - 10 business days* |
220.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Dienestrol is a synthetic non-steroidal estrogen receptor (ER) agonist and an active metabolite... more
Product information "Dienestrol"
Dienestrol is a synthetic non-steroidal estrogen receptor (ER) agonist and an active metabolite of diethylstilbestrol (Cay-10006876). Dienestrol binds to ERalpha and ERbeta (Kis = 0.05 and 0.03 nM, respectively) and activates ERalpha in a reporter assay (EC50 = 3.23 nM). It also inhibits porcine microtubule assembly and induces disassembly of preformed microtubules when used at concentrations of 50 and 100 µM, respectively, in cell-free assays. Oral administration of dienestrol (1.5-6.25 µg/kg) to pregnant rats during gestation and lactation decreases sperm motility and viability and induces prostatitis in mature male offspring. It induces abortions when administered to pregnant rats at 50 and 75 µg/kg. Formulations containing dienestrol have been used in the treatment of atrophic vaginitis and vulvar atrophy.Formal Name: 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-phenol. CAS Number: 84-17-3. Synonyms: Dienoestrol, NSC 59809. Molecular Formula: C18H18O2. Formula Weight: 266.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: OC1=CC=C(C(C(C2=CC=C(C=C2)O)=CC)=CC)C=C1. InChi Code: InChI=1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3. InChi Key: NFDFQCUYFHCNBW-UHFFFAOYSA-N.
Keywords: | Dienoestrol, NSC 59809, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-phenol |
Supplier: | Cayman Chemical |
Supplier-Nr: | 38954 |
Properties
Application: | Diethylstilbestrol active metabolite, synthetic non-steroidal estrogen receptor agonist |
MW: | 266.3 D |
Formula: | C18H18O2 |
Purity: | >95% |
Format: | Solid |
Database Information
CAS : | 84-17-3| Matching products |
KEGG ID : | K08551 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H350, H361 |
P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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