Deucravacitinib

Item number	Size	Delivery time	Price
TGM-T14687-1mg	1 mg	7 - 10 business days*	63.00€
TGM-T14687-5mg	5 mg	7 - 10 business days*	154.00€
TGM-T14687-1mL	1 ml	7 - 10 business days*	167.00€
TGM-T14687-10mg	10 mg	7 - 10 business days*	287.00€
TGM-T14687-25mg	25 mg	7 - 10 business days*	453.00€
TGM-T14687-50mg	50 mg	7 - 10 business days*	671.00€
TGM-T14687-100mg	100 mg	7 - 10 business days*	956.00€
TGM-T14687-200mg	200 mg	7 - 10 business days*	1,289.00€
TGM-T14687-500mg	500 mg	7 - 10 business days*	1,921.00€

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Description: Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2].... more

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Product information "Deucravacitinib"

Description: Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Target: Interleukin, Tyrosine Kinases, IFNAR, JAK. Smiles: [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncn(C)n2)c1OC. References: Wrobleski ST, et al. Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. J Med Chem. 2019 Jul 18.

Keywords:	BMS-986165
Supplier:	TargetMol
Supplier-Nr:	T14687

Properties

Application:	Targets non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] (TYK2)
MW:	425.46 D
Formula:	C20H19D3N8O3

Database Information

CAS :	1609392-27-9\| Matching products
KEGG ID :	K11219 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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