Denagliptin tosylate

Description: Denagliptin (GW823093 or GSK-823093) is a dipeptidyl peptidase IV (DPP-IV) inhibitor. Target: Others. Smiles: S(=O)(=O)(O)C1=CC=C(C)C=C1.C([C@@H](C(=O)N1[C@H](C#N)C[C@H](F)C1)N)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3. References: De Serres M, Bowers G, Boyle G, Beaumont C, Castellino S, Sigafoos J, Dave M, Roberts A, Shah V, Olson K, Patel D, Wagner D, Yeager R, Serabjit-Singh C. Evaluation of a chimeric (uPA+/+)/SCID mouse model with a humanized liver for prediction of human metabolism. Xenobiotica. 2011 Jun,41(6):464-75. doi: 10.3109/00498254.2011.560295. Epub 2011 Mar 4. PubMed PMID: 21370990.