Demegestone

Description: Demegestone is a progestin, or a synthetic progestogen, and hence is a progesterone receptor agonist, the biological target of progestogens like progesterone. It has no androgenic activity. Previously used to treat luteal insufficiency. Target: Others. Smiles: C[C@@]12[C@]([C@]3(C(=C4C(CC3)=CC(=O)CC4)CC1)[H])(CC[C@@]2(C(C)=O)C)[H]. References: Pugeat M, Lejeune H, Dechaud H, Brébant C, Mallein R, Tourniaire J. [Luteal insufficiency and elevation of sex-binding proteins by demegestone]. Rev Fr Gynecol Obstet. 1988 Jul-Sep,83(7-9):495-8. French. PubMed PMID: 3194612.