Dasatinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Dasatinib (BMS-354825) is an orally active, ATP-competitive tyrosine kinase... more
Product information "Dasatinib"
Description: Dasatinib (BMS-354825) is an orally active, ATP-competitive tyrosine kinase inhibitor that targets Src and Bcr-Abl (Ki=16/30 pM), with antitumor activity, used in the treatment of leukemia and lymphoma. Target: c-Kit, Autophagy, Bcr-Abl, Apoptosis, Src. Smiles: N(C1=CC(N2CCN(CCO)CC2)=NC(C)=N1)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3. References: Chan CM, et al. Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis. Clin Cancer Res. 2012 Jul 1,18(13):3580-91.
| Keywords: | BMS-354825 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1448 |
Properties
| Application: | Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1) |
| MW: | 488.01 D |
| Formula: | C22H26ClN7O2S |
Database Information
| CAS : | 302962-49-8| Matching products |
| KEGG ID : | K05089 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H318, H351, H361, H372, H410 |
| P Phrases: | P201, P202, P260, P264, P270, P273, P280, P310, P314, P321, P391, P302+P352, P305+P351+P338, P308+P313, P332+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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