D-Serine

D-Serine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay31197-25 25 g -

6 - 10 business days*

111.00€
Cay31197-50 50 g -

6 - 10 business days*

196.00€
Cay31197-100 100 g -

6 - 10 business days*

305.00€
Cay31197-250 250 g -

6 - 10 business days*

649.00€
 
D-Serine is the dextrorotary isomer of the non-essential amino acid L-serine and a co-agonist of... more
Product information "D-Serine"
D-Serine is the dextrorotary isomer of the non-essential amino acid L-serine and a co-agonist of NMDA receptors. It is formed by conversion of L-serine by serine racemase and found primarily in the brain. D-Serine binds to the glycine site of the NMDA receptor and potentiates glutamate-induced currents in oocytes expressing various subunit combinations (EC50s = 0.17-0.32 µM) more potently than glycine. It reverses deficits in prepulse inhibition with prepulses of 69 and 73 decibels (dB), but not 81 dB, and increases the time spent in the target quadrant of the Morris water maze in mice with a mutant form of serine racemase (SrrY269*) when administered at a dose of 600 mg/kg. Serum levels of D-serine are decreased in patients with schizophrenia.CAS Number: 312-84-5. Synonyms: NSC 77689, (R)-Serine. Molecular Formula: C3H7NO3. Formula Weight: 105.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 5 mg/ml. SMILES: OC[C@@H](N)C(O)=O. InChi Code: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1. InChi Key: MTCFGRXMJLQNBG-UWTATZPHSA-N.
Keywords: (R)-Serine, NSC 77689
Supplier: Cayman Chemical
Supplier-Nr: 31197

Properties

Application: NMDA co-agonist
MW: 105.1 D
Formula: C3H7NO3
Purity: >95%
Format: Solid

Database Information

CAS : 312-84-5| Matching products
KEGG ID : K05208 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "D-Serine"
Write a review
or to review a product.
Viewed