Cyclosporin A (5x100mg)

Cyclosporin A (5x100mg)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-CN2-0079-M100 100 mg -

3 - 9 business days*

55.00€
AG-CN2-0079-5100 500 mg (5 x 100 mg) -

3 - 9 business days*

165.00€
AG-CN2-0079-G001 1 g -

3 - 9 business days*

187.00€
 
Potent immunosuppressant (same as FK-506 (Prod. No. AG-CN2-0047) and rapamycin (Prod. No.... more
Product information "Cyclosporin A (5x100mg)"
Potent immunosuppressant (same as FK-506 (Prod. No. AG-CN2-0047) and rapamycin (Prod. No. AG-CN2-0025)) - Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B, calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells (NFAT) transcription factor, leading to disruption of T cell activation - Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2) - Prevents rejection of transplanted organs - Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis) - Antibacterial. Antifungal. Antiparasitic - Apoptosis inhibitor. Inhibits the mitochondrial permeability transition pore (MPTP) from opening, thus inhibiting cytochrome c release - NF-kappaB suppressor by induction of unfolded protein response (UPR) - Anti-cancer compound. Apoptosis and autophagy inducer - Inhibits nitric oxide synthesis induced by interleukin-1alpha, lipopolysaccharides and TNF-alpha.
Keywords: Antibiotic S 7481F1, Ciclosporin A, CsA, Cyclosporine, NSC 290193, Ramihyphin A
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-CN2-0079

Properties

Application: Immunsuppressant
MW: 1202,6 D
Formula: C62H111N11O12
Purity: >98%
Format: Solid

Database Information

CAS : 59865-13-3| Matching products
KEGG ID : K06268 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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