Cucurbitacin IIA
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance... more
Product information "Cucurbitacin IIA"
Description: 1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3. Target: Apoptosis, Survivin. Smiles: [H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O. References: He J , Wang Y , Xu L H , et al. Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages[J]. International Immunopharmacology, 2013, 16(1):27-34.
| Keywords: | Hemslecin A, Curcurbitacin IIA, Dihydrocucurbitacin Q1 |
| Supplier: | TargetMol |
| Supplier-Nr: | T3S1471 |
Properties
| MW: | 562.73 D |
| Formula: | C32H50O8 |
Database Information
| CAS : | 58546-34-2| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H300 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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