CU-CPT9b

Item number	Size	Manual	Delivery time	Price
TGM-T7302-1mg	1 mg	-	7 - 10 business days*	44.00€
TGM-T7302-5mg	5 mg	-	7 - 10 business days*	96.00€
TGM-T7302-1mL	1 ml	-	7 - 10 business days*	130.00€
TGM-T7302-10mg	10 mg	-	7 - 10 business days*	159.00€
TGM-T7302-25mg	25 mg	-	7 - 10 business days*	267.00€
TGM-T7302-50mg	50 mg	-	7 - 10 business days*	388.00€
TGM-T7302-100mg	100 mg	-	7 - 10 business days*	584.00€

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Description: CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8... more

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Product information "CU-CPT9b"

Description: CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8, Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM. Target: TLR. Smiles: Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12. References: Zhang S , Hu Z , Tanji H , et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology, 2017, 14(1):58-64.

Keywords:	CU-CPT-9b, TLR8-specific antagonist 1
Supplier:	TargetMol
Supplier-Nr:	T7302

Properties

Application:	TLR8 antagonist
MW:	251.28 D
Formula:	C16H13NO2

Database Information

CAS :	2162962-69-6\| Matching products
KEGG ID :	K10170 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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