CU-CPT9b

CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8, Kd = 21 nM). It inhibits activation of NF-?B induced by the TLR8 agonist R-848 (Cay-14806) in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.Formal Name: 4-(4-hydroxy-3-methylphenyl)-7-quinolinol. CAS Number: 2162962-69-6. Molecular Formula: C16H13NO2. Formula Weight: 251.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 238 nm. SMILES: OC1=CC2=C(C=C1)C(C3=CC=C(O)C(C)=C3)=CC=N2. InChi Code: InChI=1S/C16H13NO2/c1-10-8-11(2-5-16(10)19)13-6-7-17-15-9-12(18)3-4-14(13)15/h2-9,18-19H,1H3. InChi Key: QXFYDRYRLOHSBD-UHFFFAOYSA-N.