CU-115

Item number	Size	Manual	Delivery time	Price
TGM-T9645-1mg	1 mg	-	7 - 10 business days*	52.00€
TGM-T9645-2mg	2 mg	-	7 - 10 business days*	86.00€
TGM-T9645-5mg	5 mg	-	7 - 10 business days*	174.00€
TGM-T9645-1mL	1 ml	-	7 - 10 business days*	218.00€
TGM-T9645-10mg	10 mg	-	7 - 10 business days*	280.00€
TGM-T9645-25mg	25 mg	-	7 - 10 business days*	512.00€
TGM-T9645-50mg	50 mg	-	7 - 10 business days*	717.00€
TGM-T9645-100mg	100 mg	-	7 - 10 business days*	970.00€

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Description: CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM... more

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Product information "CU-115"

Description: CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-alpha and IL-1beta activated by R-848 in THP-1 cells. Target: TLR. Smiles: Fc1cccc(I)c1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1. References: Rosaura Padilla-Salinas, et al. Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors 7 and 8. J Med Chem. 2019 Nov 27,62(22):10221-10244.

Keywords:	N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide
Supplier:	TargetMol
Supplier-Nr:	T9645

Properties

Application:	TLR8 antagonist
MW:	569.21 D
Formula:	C21H11F7INO2

Database Information

CAS :	2471982-20-2\| Matching products
KEGG ID :	K10170 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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