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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay14601-10 | 10 mg | - |
6 - 10 business days* |
163.00€
|
|||
| Cay14601-50 | 50 mg | - |
6 - 10 business days* |
644.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
(±)-Cromakalim is a prototypical activator of the ATP-sensitive potassium channel, SUR2-Kir6,... more
Product information "(±)-Cromakalim"
(±)-Cromakalim is a prototypical activator of the ATP-sensitive potassium channel, SUR2-Kir6, that displays anti-ischemic (EC25 = 8.9 µM) and cardioprotective (IC50 = 0.03 µM) effects in rat hearts. (±)-Cromakalim has also been shown to relax bladder smooth muscle in vitro. It has been used to investigate potassium channel biology and as a scaffold to develop increasingly selective K+ channel openers with clinical relevance.Formal Name: (3R,4S)-rel-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile. CAS Number: 94470-67-4. Synonyms: BRL 34915. Molecular Formula: C16H18N2O3. Formula Weight: 286.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 50 mM. SMILES: CC1(C)[C@@H](O)[C@H](N2CCCC2=O)C3=C(C=CC(C#N)=C3)O1. InChi Code: InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/m1/s1. InChi Key: TVZCRIROJQEVOT-CABCVRRESA-N.
| Keywords: | BRL 34915, (3R,4S)-rel-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 14601 |
Properties
| Application: | SUR2-Kir6 activator |
| MW: | 286.3 D |
| Formula: | C16H18N2O3 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 94470-67-4| Matching products |
| KEGG ID : | K05004 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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