Conduritol B epoxide

Conduritol B epoxide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15216-5 5 mg -

6 - 10 business days*

73.00€
Cay15216-25 25 mg -

6 - 10 business days*

208.00€
Cay15216-50 50 mg -

6 - 10 business days*

344.00€
 
Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid... more
Product information "Conduritol B epoxide"
Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid beta-glucosidase, glucosylceramidase, GBA, or GBA1 (IC50 = 9 µM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic beta-glucosidase. As glucocerebrosidase deficiency results in Gaucher disease, a common lysosomal storage disorder that can involve defects in blood, bone, neurological, and liver development, CBE is used in in vitro and animal models of the disease.Formal Name: 1,2-anhydro-myo-inositol. CAS Number: 6090-95-5. Synonyms: CBE. Molecular Formula: C6H10O5. Formula Weight: 162.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H]2[C@@H]1O2. InChi Code: InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1. InChi Key: ZHMWOVGZCINIHW-FTYOSCRSSA-N.
Keywords: CBE, 1,2-anhydro-myo-inositol
Supplier: Cayman Chemical
Supplier-Nr: 15216

Properties

Application: Irreversible glucocerebrosidase inhibitor
MW: 162.1 D
Formula: C6H10O5
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 6090-95-5| Matching products
KEGG ID : K01201 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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