COH000
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: COH000 is a covalent and irreversible inhibitor of small ubiquitin-like modifier... more
Product information "COH000"
Description: COH000 is a covalent and irreversible inhibitor of small ubiquitin-like modifier (SUMO)-activating enzyme and inhibited SUMOylation (IC50: ~ 0.2 µM in vitro). Target: E1/E2/E3 Enzyme. Smiles: [H][C@]12O[C@@](C=C1)([C@@H](Cc1ccc(C)cc1)Nc1ccccc1)C(C(=O)OC)=C2C(=O)OC. References: Li YJ, et al. Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme. Cell Chem Biol. 2018 Dec 5. pii: S2451-9456(18)30386-6.
| Supplier: | TargetMol |
| Supplier-Nr: | T5199 |
Properties
| Application: | SUMO-activating enzyme inhibitor |
| MW: | 419.47 D |
| Formula: | C25H25NO5 |
Database Information
| CAS : | 1534358-79-6| Matching products |
| KEGG ID : | K10684 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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