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![Cloxacillin-13C4 (sodium salt)](https://www.biomol.com/media/image/b0/8f/76/Cay28801-1_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay28801-1 | 1 mg | - |
6 - 10 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cloxacillin-13C4 is intended for use as an internal standard for the quantification of... more
Product information "Cloxacillin-13C4 (sodium salt)"
Cloxacillin-13C4 is intended for use as an internal standard for the quantification of cloxacillin (Cay-22249) by GC- or LC-MS. Cloxacillin is a beta-lactam antibiotic and a derivative of oxacillin (Cay-23954). It is active against clinical isolates of the Gram-positive bacteria S. aureus and S. epidermidis (MICs = 0.004-0.4 and 0.1-0.8 µg/ml, respectively) but not 34 Gram-negative bacteria (MICs = >128 µg/ml for all)., Cloxacillin binds to S. aureus penicillin-binding protein 1 (PBP1), PBP2, PBP3, and PBP4 (IC50s = 0.04, 0.12, 0.21, and 2.5 µg/ml, respectively). It also binds to recombinant type Ib penicillinase, as well as P. vulgaris and C. freundii cephalosporinase (Kis = 15, 0.27, and 0.027 µM, respectively). Cloxacillin decreases the number of staphylococci in the mammary gland in a mouse model of acute, but not chronic, mastitis induced by Staphylococcus infection.Formal Name: (2S,5R,6R)-6-(3-(2-chlorophenyl)-5-(methyl-13C)isoxazole-4-carboxamido-13C)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, monosodium salt. Molecular Formula: C15[13C4]H17ClN3O5S . Na. Formula Weight: 461.8. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble, Water: slightly soluble. SMILES: CC1(C)[C@H](C([O-])=O)N2C([C@@H](N[13C]([13C]3=[13C]([13CH3])ON=C3C4=CC=CC=C4Cl)=O)[C@@]2([H])S1)=O.[Na+]. InChi Code: InChI=1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23,/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27),/q,+1/p-1/t13-,14+,17-,/m1./s1/i1+1,8+1,11+1,15+1,. InChi Key: SCLZRKVZRBKZCR-QSLPWVMZSA-M.
Keywords: | (2S,5R,6R)-6-(3-(2-chlorophenyl)-5-(methyl-13C)isoxazole-4-carboxamido-13C)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, monosodium salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 28801 |
Properties
Application: | GC-MS, LC-MS, Internal standard, Antibiotic, Beta-lactamase inhibitor |
MW: | 461.8 D |
Formula: | C15[13C4]H17ClN3O5S . Na |
Purity: | >95% |
Format: | Solid |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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