Clinafloxacin (hydrochloride)

Clinafloxacin is a fluoroquinolone antibiotic that displays broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).Formal Name: 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride. CAS Number: 105956-99-8. Synonyms: AM1091. Molecular Formula: C17H17ClFN3O3 . HCl. Formula Weight: 402.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Methanol: 1 mg/ml (warmed). lambdamax: 219, 240, 295, 344 nm. SMILES: OC(C1=CN(C2CC2)C3=C(Cl)C(N4CCC(N)C4)=C(F)C=C3C1=O)=O.Cl. InChi Code: InChI=1S/C17H17ClFN3O3.ClH/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9,/h5,7-9H,1-4,6,20H2,(H,24,25),1H. InChi Key: BMACYHMTJHBPOX-UHFFFAOYSA-N.