cis-10-hydroxy Nortriptyline
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cis-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants... more
Product information "cis-10-hydroxy Nortriptyline"
cis-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Cay-15881) and nortriptyline (Cay-15904). It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6. cis-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices (EC50 = 160 nM).Formal Name: (5Z)-10,11-dihydro-5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-10-ol. CAS Number: 47132-19-4. Synonyms: 10(Z)-hydroxy Nortriptyline. Molecular Formula: C19H21NO. Formula Weight: 279.4. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml, DMSO: 10 mg/ml, Ethanol: 5 mg/ml. SMILES: CNCC/C=C1C2=CC=CC=C2C(CC3=CC=CC=C3\1)O. InChi Code: InChI=1S/C19H21NO/c1-20-12-6-11-16-15-8-3-2-7-14(15)13-19(21)18-10-5-4-9-17(16)18/h2-5,7-11,19-21H,6,12-13H2,1H3/b16-11-. InChi Key: VAGXZGJKNUNLHK-WJDWOHSUSA-N.
| Keywords: | 10(Z)-hydroxy Nortriptyline, (5Z)-10,11-dihydro-5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-10-ol |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 36659 |
Properties
| Application: | Amitriptyline / nortriptyline active metabolite |
| MW: | 279.4 D |
| Formula: | C19H21NO |
| Purity: | >90% |
| Format: | Solid |
Database Information
| CAS : | 47132-19-4| Matching products |
| KEGG ID : | K17712 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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