Ciprofloxacin-d8 (hydrochloride)

Ciprofloxacin-d8 (hydrochloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay25466-500 500 µg -

6 - 10 business days*

98.00€
Cay25466-1 1 mg -

6 - 10 business days*

155.00€
Cay25466-5 5 mg -

6 - 10 business days*

479.00€
 
Ciprofloxacin-d8 is intended for use as an internal standard for the quantification of... more
Product information "Ciprofloxacin-d8 (hydrochloride)"
Ciprofloxacin-d8 is intended for use as an internal standard for the quantification of ciprofloxacin (Cay-14286) by GC- or LC-MS. Ciprofloxacin is a fluoroquinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae, and H. pylori (MIC50s = 0.004-1 µg/ml). It is also active against clinical isolates of Bacteroides, Fusobacterium, Eubacterium, Actinomyces, Peptococcus, Peptostreptococcus, and Streptococcus in vitro (MIC50s = 0.5-2 µg/ml). Ciprofloxacin inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 13.5 and 5.76 µg/ml, respectively). It reduces mortality in mouse models of intraperitoneal E. coli, P. vulgaris, K. pneumoniae, P. aeruginosa, and S. aureus infection (ED90-100s = 1-5, 2.5-5, 5-10, 20-40, and 80 mg/kg, respectively) and prevents mortality in a mouse model of subcutaneous S. typhimurium infection at 10 mg/kg. Formulations containing ciprofloxacin have been used in the treatment of bacterial infections.Formal Name: 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-1,4-dihydroquinoline-3-carboxylic acid, monohydrochloride. CAS Number: 1216659-54-9. Molecular Formula: C17H10D8FN3O3 . HCl. Formula Weight: 375.9. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solid. Solubility: Methanol: Slightly Soluble, Water: Slightly Soluble. SMILES: FC1=CC2=C(C=C1N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])N(C4CC4)C=C(C(O)=O)C2=O.Cl. InChi Code: InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24,/h7-10,19H,1-6H2,(H,23,24),1H/i3D2,4D2,5D2,6D2,. InChi Key: DIOIOSKKIYDRIQ-JCYLEXHWSA-N.
Keywords: 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-1,4-dihydroquinoline-3-carboxylic acid, monohydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 25466

Properties

Application: Antibiotic, GC-MS, LC-MS, Internal standard
MW: 375.9 D
Formula: C17H10D8FN3O3 . HCl
Purity: >99% deuterated forms (d1-d8)
Format: Solid

Database Information

CAS : 1216659-54-9| Matching products
KEGG ID : K02469 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H319, H400, H410
P Phrases: P264, P273, P280, P305+351+338, P337+313, P391, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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