Cilastatin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase... more
Product information "Cilastatin"
Description: Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. Target: Proteasome, Antibacterial, Antibiotic. Smiles: CC1(C)C[C@@H]1C(=O)N\C(=C/CCCCSC[C@H](N)C(O)=O)C(O)=O. References: Farrell CA, et al. Arch Biochem Biophys. 1987 Jul,256(1):253-9.
| Keywords: | MK0791 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2583 |
Properties
| Application: | Targets membrane dipeptidase [EC:3.4.13.19] (DPEP) |
| MW: | 358.45 D |
| Formula: | C16H26N2O5S |
Database Information
| CAS : | 82009-34-5| Matching products |
| KEGG ID : | K01273 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H312, H332 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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