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CI-898 HCl

TargetMol
CI-898 HCl
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T70304-25mg 25 mg

7 - 10 business days*

1,491.00€
TGM-T70304-50mg 50 mg

7 - 10 business days*

1,943.00€
TGM-T70304-100mg 100 mg

7 - 10 business days*

2,453.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Description: CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR).... more
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Product information "CI-898 HCl"
Description: CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine (6-TG) in mice with advanced stage P338 leukemia. Target: Others. Smiles: Cl.Cl.Cl.COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC
Supplier: TargetMol
Supplier-Nr: T70304

Properties

Application: Lipophilic antifolate DHFR inhibitor
MW: 478.8 D
Formula: C19H26Cl3N5O3

Database Information

CAS : 1658520-97-8| Matching products
KEGG ID : K00287 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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